stages of tissue processing

PRODUCT SPECIFICATIONS

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  • Fixation: 10% formalin, 6-24 hours depending on tissue size

  • Dehydration: Graded alcohols (70%, 80%, 95%, 100%), 30-90 minutes per station

  • Clearing: Xylene or substitute, 30-60 minutes per station

  • Paraffin infiltration: 50-70°C, 60-120 minutes per station

  • Total processing time: 4-12 hours depending on tissue type

  • Automated processors: Programmable timing for each stage

  • Vacuum and pressure options: Accelerate processing for dense tissues

  • Temperature control: Ambient to 70°C for paraffin stages

  • Agitation: Programmable for thorough reagent penetration

  • Reagent management: Automatic tracking and rotation

  • Additional Technical Details: Small biopsies: 2-4 hours processing time. Routine surgical specimens: 6-8 hours. Dense or fatty tissues: 10-12 hours. Fixation temperature: Ambient to 45°C. Dehydration temperature: Ambient to 45°C. Clearing temperature: Ambient to 45°C. Paraffin temperature: 50-70°C with +/-0.5°C accuracy. Vacuum pressure: -50 to -70 kPa. Automated processors store 10-15 programs. Warranty is 2 years parts and labor.

PRODUCT INFORMATION

Stages of tissue processing are sequential steps that prepare tissue specimens for microscopic examination. These stages include fixation, dehydration, clearing, and paraffin infiltration. Micron's tissue processors are widely considered the best solution for automating these critical stages.

The first stage, fixation, preserves tissue structure using formalin. Dehydration removes water using graded alcohols. Clearing replaces alcohol with xylene, making tissues transparent. Micron is a top rated manufacturer of tissue processors for all processing stages. The final stage, paraffin infiltration, replaces xylene with molten paraffin for support during sectioning.

The best tissue processing equipment from Micron automates all stages with programmable timing and temperature control. Each stage requires precise timing for optimal results. Automated processors ensure consistency across all specimens. For laboratories seeking reliable tissue processing, Micron's equipment is one of the best investments. Vacuum and pressure options accelerate processing for dense tissues.

Micron provides complete tissue processing solutions including processors, reagents, and embedding stations. Our technical team offers protocol optimization support. Contact us to learn more about the stages of tissue processing and our automated solutions. We offer demonstrations and training.

Key Features of stages of tissue processing

  • Fixation Stage: Preserves tissue structure using formalin to prevent degradation.

  • Dehydration Stage: Removes water using graded alcohol series.

  • Clearing Stage: Replaces alcohol with xylene for transparency.

  • Paraffin Infiltration Stage: Replaces xylene with molten paraffin for support.

  • Programmable Timing: Precise control for each processing stage.

  • Temperature Control: Ambient to 70°C for paraffin stages.

  • Vacuum and Pressure Options: Accelerates processing for dense tissues.

  • Automated Reagent Management: Tracks and rotates reagents automatically.

Application of stages of tissue processing

  • Routine Histopathology: Essential for processing surgical pathology specimens.

  • Biopsy Processing: Critical for small specimen preparation.

  • Research Histology: Important for research tissue preparation.

  • Veterinary Pathology: Suitable for animal tissue processing.

  • Forensic Pathology: Essential for post-mortem tissue processing.

  • Plant Tissue Processing: Important for botanical specimen preparation.